Enantiomer ( Chiral ) Separation Chromatography - Features & Application Examples
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ULTRON ES-OVM-3
Stationary Phase : Ovomucoid
https://en.wikipedia.org/wiki/Ovomucoid
Features:
・Maximum operating pressure of 30 MPa.
・Can be used in LC/MS systems as well.
・Employs a 3 µm packing material for higher peak resolution and theoretical
plate numbers.
・Enables significant reductions in analysis times while maintaining high
theoretical plate numbers.
・Enables further improvements in performance with optimization of LC system
tubing and flow cells.
・9 column length and inner diameter combinations available.
Applications
・Pharmaceuticals ・Pesticides ・Organic synthetic compounds
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ULTRON ES-OVM, ULTRON ES-OVM-C
Stationary Phase : Ovomucoid
https://en.wikipedia.org/wiki/Ovomucoid
Features:
・Employ a highly denaturation resistant protein (ovomucoid) ligand.
・Display a wide range of chiral recognition.
・No sample pretreatment required for chiral separations.
・Can be used for reversed-phase analyses. ・Trace analyses possible (several
nanograms).
・[ULTRON ES-OVM-C] Clopidogrel bisulfate evaluation conditions based on USP
standards employed for shipping inspections.
・[ULTRON ES-OVM-C] Low viscosity 30% acetonitrile aqueous solution used as
column storage solvent.
Applications
・Pharmaceuticals ・Pesticides ・Organic synthetic compounds
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Applications
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Samples, Wiki-Inf
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Chromatograms
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LC
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(1S,2R)-1-Methyl cis-1,2,3,6-Tetrahydrophthalate
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(1S,2R)-1-Methyl
cis-1,2,3,6-Tetrahydrophthalate
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LC
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1,2-Diphenylethylamine
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1,2-Diphenylethylamine
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LC
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Oxprenolol
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Oxprenolol
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LC
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β-Blocking agent
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Bunitrolol
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LC
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closed
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LC
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β-Blocking agent
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Arotinolol
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LC
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β-Blocking agent
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Pindolol
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LC
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β-Blocking agent
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Propranolol
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LC
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The effect of the column temperature (Propranolol)
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Propranolol
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LC
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Calcium rivalry medicine
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Bay K 8644
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LC
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Calcium rivalry medicine
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Verapamil
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LC
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Calcium rivalry medicine
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Prenylamine
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LC
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Bronchodilator agent
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Clorprenaline
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LC
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The local anesthetic
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Bupivacaine
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LC
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Muscle relaxant
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Chlormezanone
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LC
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Muscle relaxant
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Tolperisone
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LC
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Antihypertensive diuretic
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Ethiazide
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LC
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Analysis of the antidepressive drug
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Trimipramine Maleate
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LC
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Flurbiprofen
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Flurbiprofen
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LC
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Ibuprofen
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Ibuprofen
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LC
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Antiinflammatory agent
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Ketoprofen
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LC
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Antiinflammatory agent
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Pranoprofen
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LC
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Antiinflammatory agent
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Zaltoprofen
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LC
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closed
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LC
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Anticholinergic agent
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Mepenzolate bromide
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LC
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Antipsychotic drug
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Thioridazine
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LC
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Antiepileptic
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Mephobarbital
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LC
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Antiepileptic
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Acetylpheneturide
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LC
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Antiparkinsonic agent
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Biperiden
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LC
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Antiparkinsonic agent
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Profenamine
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LC
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Antiparkinsonic agent
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Trihexyphenidyl
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LC
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Antihistaminic drug
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Alimemazine
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LC
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Antihistaminic drug
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Chlorpheniramine
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LC
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Antihistaminic drug
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Dimethindene maleate
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LC
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Antihistaminic drug
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Homochlorcyclizine
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LC
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Antihistaminic drug
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Promethazine
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LC
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Antianxiety agent
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Hydroxyzine
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LC
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Disopyramide phosphate
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Disopyramide phosphate
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LC
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Hypnotic
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Glutethimide
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LC
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Hypnotic
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Hexobarbital
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LC
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Peptic ulcer agent
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Proglumide
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LC
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closed
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LC
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Thyroxine
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Thyroxine
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LC
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Antitussive drug
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Benproperine
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LC
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Meclizine
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Meclizine
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LC
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Application to pharmacokinetics analysis using the narrow bore column
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Warfarin
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LC
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Flavonoid
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Flavanone
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LC
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Benzoin
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Benzoin
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LC
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Muscle relaxant
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Chlorphenesin
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LC
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Muscle relaxant
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Eperisone
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LC
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Antitussive drug
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Cloperastine
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LC
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The effect of the column temperature (Maleic acid trimipramine)
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Trimipramine Maleate
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LC
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2-(4-Hydroxyphenoxy)propionic acid
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2-(4-Hydroxyphenoxy)propionic acid
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LC
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3,3-dimethyl-4-phenyl-2-azetidinone
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3,3-dimethyl-4-phenyl-2-azetidinone
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LC
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Aminoglutethimide
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Aminoglutethimide
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LC
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Amlodipine
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Amlodipine
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LC
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Benidipine Hydrochloride
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Benidipine Hydrochloride
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LC
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Bepotastine Besilate
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Bepotastine Besilate
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LC
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Bepridil hydrochloride
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Bepridil hydrochloride
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LC
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Bicalutamide
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Bicalutamide
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LC
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Bromacil
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Bromacil
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LC
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Brompheniramine maleate
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Brompheniramine maleate
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LC
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Candesartan Cilexetil
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Candesartan Cilexetil
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LC
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Cyclobenzaprine Hydrochloride
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Cyclobenzaprine Hydrochloride
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LC
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Duloxetine Hydrochloride
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Duloxetine Hydrochloride
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LC
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EDDP perchlorate
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EDDP perchlorate
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LC
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Ezetimibe
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Ezetimibe
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LC
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Omeprazole
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Omeprazole
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LC
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Ornidazole
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Ornidazole
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LC
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Amlodipine
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Amlodipine
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LC
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Atomoxetine Hydrochloride
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Atomoxetine Hydrochloride
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LC
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Atomoxetine Hydrochloride
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Atomoxetine Hydrochloride
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LC
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Azelnidipine
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Azelnidipine
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LC
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Bupropion Hydrochloride
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Bupropion Hydrochloride
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LC
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Candesartan Cilexetil
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Candesartan Cilexetil
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LC
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Carvedilol
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Carvedilol
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LC
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Carvedilol
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Carvedilol
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LC
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Cetirizine Hydrochloride
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Cetirizine Hydrochloride
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LC
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Cetirizine Hydrochloride
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Cetirizine Hydrochloride
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LC
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Doxylamine succinate
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Doxylamine succinate
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LC
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Duloxetine Hydrochloride
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Duloxetine Hydrochloride
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LC
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Escitalopram Oxalate
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Escitalopram Oxalate
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LC
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Formoterol Fumarate
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Formoterol Fumarate
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LC
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Formoterol Fumarate
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Formoterol Fumarate
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LC
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Ibuprofen
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Ibuprofen
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ULTRON ES-PEPSIN
Stationary Phase : Pepsin
https://en.wikipedia.org/wiki/Pepsin
Features:
・Employs the polypeptide splitting enzyme pepsin
(obtained from pig stomach linings), which is chemically bonded to the base
material in an extremely stable manner.
・Displays superior performance with respect to chiral
separations of aminoalcohol pharmaceuticals such as beta blockers.
・No sample pretreatment required for chiral separations.
・Can be used for reversed-phase analyses.
・Trace analyses possible (several nanograms).
Applications
・Pharmaceuticals ・Pesticides ・Organic synthetic compounds
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