Preparative Chromatography Column
Media(Packing Materials)
Rather than analysis purposes, the Preparative chromatography is used to purify
sufficient quantities of a substance for further use, ........
https://en.wikipedia.org/wiki/Chromatography
Preparative
Chromatography Technology
As the drug and food safety issues have growing concerns, the general public,
industry and regulatory have become increasingly demanding for the quality and
purity of drug and functional food and traditional techniques and methods has
been difficult to meet the high performance purification and separation needs,
particularly in drug and functional food fields.
The preparative chromatography technology, with its unique features of high
selectivity and excellent process stability, has become the ideal solution to
the separation and purification demands that increase persistantley and rapidly
in a variety of practical applications,
and has become one of the major technical requirements for the development and
upgrading of the pharmaceutical and bio-chemical industries.
The sizes of Preparative Purification is denoted as
Semi-preparation, Pilot and Industrial process scales.
Comprehensive applications:
l Target active drug molecules
l Natural pharmaceutically active
ingredients
l Bio-fermentation products
l Macromolecular drugs as peptides
and proteins
l Functional and active ingredients
of natural product
l Pharmaceutical impurities
l Reference standards
Our Team Partner:
We(ABDC) and ACChrom are global technology and sales partners,
serving application commitments for users in research institutions, industry
sections, universities, and have successfully developed high performance
preparative and analytical chromatography seperation media with globalized intellectual properties.
http://www.acchrom.com/
http://www.acchrom.com/en/
http://www.chromnet.net/
Core Construction :
The core construction of our preparative chromatography technology is based the
increasing of the selectivity of separation medium (packing material) to achieve
the chromatography resolution demand.
Various aspects including the surface bonding phase, structural design, and
surface bonding density optimization, etc., are selectively enhanced and
regulated to realize best and optimized selectivity.
We take advantages for our completely independent intelligence properties and
local R&D and manufacturing capacities,that we can respond quickly to product
delivery timing and to specific customization needs !
Features:
l
Optimized material surface to achieve superior
selectivity.
l
High loading capacity tthat improves production
efficiency, reduce process costs.
l
Excellent chemical stability ensuring
repeatability, long lifeHigh mechanical strength with a good life
and stabile column pressure.
l
Full range of packing material for various
preparation development needs.
l Customized packing material
design and production.
l
Precision bonding process ensures stable and consistent
batch qualities.
l
Excellent linear amplification capability to
achieve all kinds of optimized preparation process development.
l
From Gram to Ton production capacity.
Polar-copolymerized
technology :
l Compatible with
pure aqueous phase
l Good retention for polar compounds
l Superior peak shape in low pH without salt and ion
pair
l High loading capacity
Patent No: ZL200910012845.1
Patent Name: Preparation of chromatography media based on copolymerization
reaction on silicone surface
http://www.acchrom.com/en/Products/HPLC-Columns/SSeries/060HZ2013.html
Overloading study of basic compounds with a positively charged C18 column in
liquid chromatography
Conventional C18/C8
The high energy adsorption sites and silanol group of conventional C18 bonded
phase will cause tailing peak for alkaline compound samples, resulting very
limited loading capacity to alkaloids.
Polar-copolymerized
C18/C8
Under low pH, without salt or ion pair, perfectly symmetrical peak and very high
loading capacity are acruired for alkaloid compounds.
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Hydrophilic
interaction liquid chromatography (HILIC)
HILIC is very suitable for the efficient separation of oligosaccharides owing to
its characteristics and superiority.
The available HILIC stationary phases for separating small pharmaceuticals
include hydroxyl-, zwitterionic- or polymer-modified silica materials. However,
due to high polarity, and the structural variety of isomeric structures, the
separation technology and materials dedicated for separation of oligosaccharides
are limited.
Unique Novel Separation Materials:
Based on the excellent technology advantages in HILIC, amide-modified stationary
phase Click Amide and maltose-bonded silica material Click Mal are specially
developed by Acchrom for the separation and purification of oligosaccharides
with high resolution.
http://www.acchrom.com/en/Products/HPLC-Columns/SSeries/060H912013.html
More information, .....
Catalogue:
Preparative Chromatography Column Media(Packing Materials)
Catalogue:
Analytical Chromatography Columns
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